Studies and anecdotal accounts have suggested that the effects of pure THC (e.g. the drug Marinol) differ from those of smoking or ingesting Cannabis flower. A possible explanation for this observation is that other cannabinoids and natural plant compounds (e.g. CBD, terpenes) are modulating the effects of THC on receptors in the brain. See:

Russo, E. B. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. Aug 2011; 162(7): 1344-1364.

The terpene myrcene has some sedative effects in humans when inhaled. Some studies also report this to be more common as the dominant terpene in indica but not sativa strains. It has been postulated that myrcene may have a modulating or entourage effect on the activity of THC. 

Anecdotally, some patients have speculated that strains higher in myrcene may have more of the characteristic indica or couch-lock effect compared to sativa strains. While there is no published research to correlate different terpene profiles with different psychoactive effects on the patient, many patients are developing preferences for terpene content of marijuana products as more information becomes available.

FAQs

Why is Terpene Profile Testing Important?

When studying cannabis, it is essential to analyze its terpenes as they contribute to strains’ effects, smell, and taste. Terpenes are compounds found in all plants, including cannabis. They are responsible for the distinct aromas associated with each strain.

In addition, analyzing terpenes ensures product consistency. This helps growers and producers consistently replicate certain strains to ensure the quality of their products. Cannabis cultivators rely on terpene testing when creating or improving strains. By understanding the profiles of terpenes, cannabis growers can decide which traits to focus on during the growing process to achieve the desired characteristics.

In the end, cannabis growers can customize each strain’s therapeutic uses. Different terpenes possess properties that can be used for health purposes. For instance, some may offer pain relief or reduce nervousness, while others can help treat nausea or even increase appetite.

Factors to consider when choosing a cannabis terpene testing lab

When selecting a lab for cannabis terpene testing, it’s important to consider certain factors.

Terpene testing helps in understanding the qualities and effects of cannabis strains, so choosing a lab becomes crucial. One factor to consider is if the lab holds accreditation from recognized authorities, such as MED or CDPHE. Accreditation guarantees adherence to quality control measures.

Also, look for labs with a proven track record and experience in conducting cannabis testing and look for customer feedback. Laboratories with experience are more likely to have developed testing methods and possess an understanding of analyzing cannabis terpenes.

When assessing a laboratory, it’s important to consider its equipment and technology. Utilizing state-of-the-art equipment and advanced testing technologies can greatly improve the accuracy and efficiency of terpene analysis. The handling and storage of samples should also be evaluated. A reputable laboratory should have established protocols in place to prevent contamination and ensure sample stability during testing. They should also be able to provide results in a timely manner.

And finally, it’s crucial to check if the lab offers a range of terpenes for analysis. Analyzing terpenes provides insights into strain profiles.

How is Terpene testing performed?

Terpene testing involves a series of steps to identify and measure the terpenes in a given sample.

The first step in the process is sample preparation. This is done by grinding the plant material to ensure consistency in particle size.

The next step is extraction. The terpenes are then extracted from the cannabis sample to concentrate them for analysis. Various extraction techniques are employed, such as steam distillation, solvent extraction (such as liquid extraction or solid phase microextraction), and headspace sampling.

The final step is analysis. Once extracted, the concentrated terpene undergoes analysis through Gas Chromatography (GC) and Gas Chromatography Mass Spectrometry (GC MS), which separates individual terpenes based on their chemical properties. The process involves passing through a section where separation and detection occur. Each terpene’s retention time and peak area are measured to identify and quantify them.

Afterward, the data obtained from the analysis undergoes software processing. The software then quantifies the terpenes in the sample by considering their retention times and peak areas. The results are compiled into a terpene profile of the cannabis strain being studied. Once the analysis is completed, the laboratory generates a report about your cannabis samples’ terpene profile. This report includes not only the names of identified terpenes but their respective concentrations and additional details about their effects and characteristics.